2-Methyl-4-(morpholin-4-yl)aniline → 4-(2-Amino-pyrimidin-5-yl)-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid (2-methyl-4-morpholin-4-yl-phenyl)-amide
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[c:18]2[n:19][cH:20][c:21](-[c:22]3[c:23]4[c:27]([n:28][c:29]([N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[n:36]3)[NH:26][CH2:25][CH2:24]4)[cH:37][n:38]2)[cH:39][cH:40]1.[CH3:41][c:42]1[cH:43][c:44]([N:45]2[CH2:46][CH2:47][O:48][CH2:49][CH2:50]2)[cH:51][cH:52][c:53]1[NH2:54].[CH3:55][c:56]1[c:57]([NH:68][C:69](=[O:70])[N:71]2[CH2:72][CH2:73][c:74]3[c:75]2[n:76][c:77]([N:105]2[CH2:106][CH2:107][O:108][CH2:109][CH2:110]2)[n:78][c:79]3-[c:80]2[cH:81][n:82][c:83]([N:86]([CH2:87][c:88]3[cH:89][cH:90][c:91]([O:92][CH3:93])[cH:94][cH:95]3)[CH2:96][c:97]3[cH:98][cH:99][c:100]([O:101][CH3:102])[cH:103][cH:104]3)[n:84][cH:85]2)[cH:58][cH:59][c:60]([N:62]2[CH2:63][CH2:64][O:65][CH2:66][CH2:67]2)[cH:61]1>>[CH3:55][c:56]1[c:57]([NH:68][C:69](=[O:70])[N:71]2[CH2:72][CH2:73][c:74]3[c:75]2[n:76][c:77]([N:105]2[CH2:106][CH2:107][O:108][CH2:109][CH2:110]2)[n:78][c:79]3-[c:80]2[cH:81][n:82][c:83]([NH2:86])[n:84][cH:85]2)[cH:58][cH:59][c:60]([N:62]2[CH2:63][CH2:64][O:65][CH2:66][CH2:67]2)[cH:61]1Participants
4
Reactant 3
HCID 219550002-Methyl-4-(morpholin-4-yl)aniline
HCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine
HCID 866401344-{2-[Bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid (2-methyl-4-morpholin-4-yl-phenyl)-amideProduct 1
Sources & evidence
- ORD record
- ord-48ce94452ca3443da0e2dfb5621f37a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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