反应详情

温度

80 °C

A mixture of 0.5 gram (0.0028 mole) of 2,3-dichlorobenzylamine and 0.27 gram (0.0081 mole) of 2-chloroethylisothiocyanate in 10 mL of 1,4-dioxane was placed in a sealed reaction vial. The reaction mixture was heated to 80° C. where it stirred for about 18 hours. The reaction mixture was allowed to cool and a solid precipitate that had formed was collected by filtration. The solid was rinsed with diethyl ether and was dried under reduced pressure to yield 0.68 gram of the title compound. The NMR spectrum was consistent with the proposed structure.

1. customwas placed in a sealed reaction vial
2. temperatureto cool
3. customa solid precipitate that had formed
4. filtrationwas collected by filtration
5. washThe solid was rinsed with diethyl ether
6. customwas dried under reduced pressure