Pyridine → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-4-morpholinesulfonamide

HRID 2157156Notes

Reaction equation

HRID 2157156 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1.[O:23]1[CH2:24][CH2:25][N:26]([S:29](=[O:30])(=[O:31])[Cl:32])[CH2:27][CH2:28]1.[cH:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[cH:17][c:18]([NH:19][S:29]([N:26]4[CH2:25][CH2:24][O:23][CH2:28][CH2:27]4)(=[O:30])=[O:31])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 12798265Morpholine-4-sulfonyl chlorideHCID 579900463-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]aniline

Product 1

HCID 57990006N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-4-morpholinesulfonamide

Sources & evidence

ORD record
ord-73229f89dcd14bf796b0601e394521e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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