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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2157183Generated: October 30, 2026

1-(2-Hydroxyethyl)piperazine → 1-(5-tert-Butylisoxazol-3-yl)-3-(3-(7-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-6-methoxyquinazolin-4-yloxy)phenyl)urea

https://huagongshe.com/reaction/2157183

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant1-(5-Tert-butyl-isoxazol-3-yl)-3-{3-[7-(2-chloro-ethoxy)-6-methoxy-quinazolin-4-yloxy]-phenyl}-ureaHCID 66876530—
Product1-(5-tert-Butylisoxazol-3-yl)-3-(3-(7-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-6-methoxyquinazolin-4-yloxy)phenyl)ureaHCID 44243305—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-f0744107f17b4b88bd9bdc8f4c8ca97e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)