Acetonitrile → α-(Acetyloxy)-α-methylcyclopropaneacetonitrile

HRID 2157341Notes

Reaction equation

HRID 2157341 reaction equation
[CH3:13][C:14](=[O:15])[O:16][C:17](=[O:18])[CH3:19].[CH3:20][C:21]#[N:22].[CH:1]1([C:4]([C:5]#[N:6])([CH3:7])[O:8][Si:9]([CH3:10])([CH3:11])[CH3:12])[CH2:2][CH2:3]1.[F:23][C:24]([F:25])([F:26])[S:27]([O-:28])(=[O:29])=[O:30].[F:32][C:33]([F:34])([F:35])[S:36]([O-:37])(=[O:38])=[O:39].[F:40][C:41]([F:42])([F:43])[S:44]([O-:45])(=[O:46])=[O:47].[Sc+3:31]>>[CH:1]1([C:4]([C:5]#[N:6])([CH3:7])[O:8][C:14]([CH3:13])=[O:15])[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 7918Acetic AnhydrideHCID 588006α-Methyl-α-[(trimethylsilyl)oxy]cyclopropaneacetonitrileHCID 2758875Trifluoromethanesulfonate3×HCID 4534583Scandium, ion (Sc3+)

Product 1

HCID 21109722α-(Acetyloxy)-α-methylcyclopropaneacetonitrile

Sources & evidence

ORD record
ord-c5a5a117238d4be1b41e941b1afc641d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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