Acetonitrile → Ethyl2-[4-(4-chlorophenyl)-3-cyclopropyl-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-propionate

HRID 2157376Notes

Reaction equation

HRID 2157376 reaction equation
[Br:17][CH:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[CH3:24].[C:25](=[O:26])([O-:27])[O-:28].[CH3:31][C:32]#[N:33].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][nH:10][c:11](=[O:16])[n:12]2[CH:13]2[CH2:14][CH2:15]2)[cH:6][cH:7]1.[Cs+:29].[Cs+:30]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][n:10]([CH:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[CH3:24])[c:11](=[O:16])[n:12]2[CH:13]2[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 79040Ethyl 2-bromopropionateHCID 104967Cesium cation2×HCID 580118325-(4-chlorophenyl)-1-cyclopropyl-1,3-dihydro-2H-imidazol-2-one

Product 1

HCID 58011824Ethyl2-[4-(4-chlorophenyl)-3-cyclopropyl-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-propionate

Sources & evidence

ORD record
ord-752db12be7a14385b0cb540aca7f3ac8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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