2,2-Dimethyl-3,4-epoxy-6-cyanochroman → 4-(2-Amino-quinolin-4-yloxy)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile
Reaction equation
[CH3:1][C:2]1([CH3:15])[CH:3]2[CH:4]([c:5]3[cH:6][c:7]([C:12]#[N:13])[cH:8][cH:9][c:10]3[O:11]1)[O:14]2.[NH2:16][c:17]1[n:18][c:19]2[cH:20][cH:21][cH:22][cH:23][c:24]2[c:25]([OH:27])[cH:26]1>>[CH3:1][C:2]1([CH3:15])[CH:3]([OH:14])[CH:4]([O:27][c:25]2[c:24]3[c:19]([n:18][c:17]([NH2:16])[cH:26]2)[cH:20][cH:21][cH:22][cH:23]3)[c:5]2[cH:6][c:7]([C:12]#[N:13])[cH:8][cH:9][c:10]2[O:11]1Participants
3
Sources & evidence
- ORD record
- ord-35ea9037c0824f64b1a2cd57e20931b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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