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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2157492Generated: October 30, 2026

Dimethylformamide → 4-(Chloromethyl)-5'-(difluoromethyl)-2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-1,1'-biphenyl

https://huagongshe.com/reaction/2157492

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantThionyl ChlorideHCID 24386—
Reactant(5'-(Difluoromethyl)-2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-1,1'-biphenyl-4-yl)methanolHCID 57706435—
Product4-(Chloromethyl)-5'-(difluoromethyl)-2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-1,1'-biphenylHCID 57706458—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-17b2f80cfc8c4ec9969db55c73096452
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)