2-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-3-benzazepin-3-yl)-1-(4-methyl-piperazin-1-yl)-ethanone → 5-Chloro-2-(5-chloro-2-{8-methoxy-3-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide
Reaction equation
[Cl:25][c:26]1[cH:27][cH:28][c:29]([NH:38][c:39]2[n:40][c:41]([Cl:46])[n:42][cH:43][c:44]2[Cl:45])[c:30]([S:32](=[O:33])(=[O:34])[N:35]([CH3:36])[CH3:37])[cH:31]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:21][c:22]1[O:23][CH3:24])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([CH3:20])[CH2:18][CH2:19]1)[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:21][c:22]1[O:23][CH3:24])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([CH3:20])[CH2:18][CH2:19]1)[CH2:9][CH2:10]2)[c:41]1[n:40][c:39]([NH:38][c:29]2[cH:28][cH:27][c:26]([Cl:25])[cH:31][c:30]2[S:32](=[O:33])(=[O:34])[N:35]([CH3:36])[CH3:37])[c:44]([Cl:45])[cH:43][n:42]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-492b9c2e78734f078bba2491376b5e3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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