HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → N-allyl-5-azaisatoic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2H-Pyrido[4,3-d][1,3]oxazine-2,4(1H)-dione | HCID 10797096 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-allyl-5-azaisatoic anhydride | HCID 86595201 | — |
Reaction Steps
To a solution of 5-azaisatoic anhydride (1 mmol, Coppola, G. M. Synthesis 1980, 505) and allyl bromide (1.1 mmol) in DMF is added triethylamine (1.2 mmol) dropwise. The reaction mixture is allowed to stir at room temperature for 12 h after which time CHCl3 is added and the organic layer is washed with water, dried (MgSO4) and the solvent is evaporated to give N-allyl-5-azaisatoic anhydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193185B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-6d46e73ce85047f2bab5e918a410ba72 |
| Source note | uspto-grants-2012_06 |