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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2158034Generated: October 31, 2026

Tetrahydrofuran → 3-{1-[4-fluoro-2-(trifluoromethyl)phenyl]ethoxy}-5-[6-(hydroxymethyl)-1H-imidazo[4,5-c]pyridin-1-yl]thiophene-2-carboxamide

https://huagongshe.com/reaction/2158034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
ReactantHCID 68766308HCID 68766308—
Product3-{1-[4-fluoro-2-(trifluoromethyl)phenyl]ethoxy}-5-[6-(hydroxymethyl)-1H-imidazo[4,5-c]pyridin-1-yl]thiophene-2-carboxamideHCID 68769101—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-5123f3ae2a9f43dd9b351c9cabe142cc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)