Picolyl chloride → 2-hydroxy-N-[2-[4-[3-methyl-4-(pyridin-2-ylmethoxy)anilino]quinazolin-5-yl]oxypropyl]acetamide
Reaction equation
[Cl:1][CH2:2][c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1.[OH:9][CH2:10][C:11](=[O:12])[NH:13][CH2:14][CH:15]([CH3:16])[O:17][c:18]1[c:19]2[c:20]([NH:28][c:29]3[cH:30][c:31]([CH3:36])[c:32]([OH:35])[cH:33][cH:34]3)[n:21][cH:22][n:23][c:24]2[cH:25][cH:26][cH:27]1>>[CH2:2]([c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1)[O:35][c:32]1[c:31]([CH3:36])[cH:30][c:29]([NH:28][c:20]2[c:19]3[c:18]([O:17][CH:15]([CH2:14][NH:13][C:11]([CH2:10][OH:9])=[O:12])[CH3:16])[cH:27][cH:26][cH:25][c:24]3[n:23][cH:22][n:21]2)[cH:34][cH:33]1Participants
3
Sources & evidence
- ORD record
- ord-6fe92d9d4cb34b3aaab4538b0cc0ed3e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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