HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2158377Generated: October 30, 2026
N-methyl-2-pyrrolidone → 3-Ethynyl-5-fluoropyridin-2-amine
https://huagongshe.com/reaction/2158377
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Amino-5-fluoro-3-iodopyridine | HCID 18455974 | — |
| Reactant | HCID 178420554 | HCID 178420554 | — |
| Product | 3-Ethynyl-5-fluoropyridin-2-amine | HCID 55288620 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
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| ORD ID | ord-9ac7b44915164e92b79f9b956e2cfcd7 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
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