5-chloro-N-cyclopropylmethoxy-3,4-difluoro-2-(4-iodo-2-methylphenylamino)-benzamide → Ci-1040
Reaction equation
[Cl:114][c:115]1[c:116]([F:117])[c:118]([F:119])[c:120]([NH:121][c:122]2[cH:123][cH:124][c:125]([I:126])[cH:127][c:128]2[CH3:129])[c:130]([C:132]([NH:133][O:134][CH2:135][CH:136]2[CH2:137][CH2:138]2)=[O:139])[cH:131]1.[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[NH:14][O:15][CH2:16][CH:17]3[CH2:18][CH2:19]3)[cH:20][c:21]([Cl:26])[c:22]([F:25])[c:23]2[F:24])[cH:4][cH:5][c:6]([I:8])[cH:7]1.[Cl:72][c:73]1[cH:74][c:75]([I:76])[cH:77][cH:78][c:79]1[NH:80][c:81]1[c:82]([F:83])[c:84]([F:85])[c:86]([Cl:87])[cH:88][c:89]1[C:90]([OH:91])=[O:92].[Cl:93][c:94]1[c:95]([F:96])[c:97]([F:98])[c:99]([NH:100][c:101]2[cH:102][cH:103][c:104]([I:105])[cH:106][c:107]2[CH3:108])[c:109]([C:111]([OH:112])=[O:113])[cH:110]1.[I:27][c:28]1[cH:29][cH:30][c:31]([NH:32][c:33]2[c:34]([F:35])[c:36]([F:37])[c:38]([Cl:39])[cH:40][c:41]2[C:42]([NH:43][O:44][CH2:45][CH:46]2[CH2:47][CH2:48]2)=[O:49])[cH:50][cH:51]1.[I:52][c:53]1[cH:54][cH:55][c:56]([NH:57][c:58]2[c:59]([F:60])[c:61]([F:62])[c:63]([Cl:64])[cH:65][c:66]2[C:67]([OH:68])=[O:69])[cH:70][cH:71]1>>[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[NH:14][O:15][CH2:16][CH:17]3[CH2:18][CH2:19]3)[cH:20][cH:21][c:22]([F:25])[c:23]2[F:24])[cH:4][cH:5][c:6]([I:8])[cH:7]1Participants
7
Reactant 6
HCID 222715295-chloro-N-cyclopropylmethoxy-3,4-difluoro-2-(4-iodo-2-methylphenylamino)-benzamide
HCID 222716432-(2-chloro4-iodophenylamino)-5-chloro-N-cyclopropylmethoxy-3,4-difluorobenzamide
HCID 222859232-(2-Chloro4-iodophenylamino)-5-chloro-3,4-difluorobenzoic acid
HCID 222861745-Chloro-3,4-difluoro-2-(4-iodo-2-methylphenylamino)-benzoic acid
HCID 222863222-(4-Iodophenylamino)-5-chloro-3,4-difluorobenzoic acid
HCID 234332002-(4-iodophenylamino)-N-cyclopropylmethoxy-5-chloro-3,4-difluorobenzamideProduct 1
Sources & evidence
- ORD record
- ord-f02e98d2f8a44f65a8252622cd9f20bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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