HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine → 2,6-Dichloro-9-[(1R,4S)-4-(5-ethyl-tetrazol-2-yl)-cyclopent-2-enyl]-9H-purine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine | HCID 58025018 | — |
| Reactant | HCID 178438076 | HCID 178438076 | — |
| Product | 2,6-Dichloro-9-[(1R,4S)-4-(5-ethyl-tetrazol-2-yl)-cyclopent-2-enyl]-9H-purine | HCID 86622800 | — |
Reaction Steps
The title compound is prepared analogously to di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine (AA3) by replacing di-t-butyliminodicarboxylate with 5-ethyltetrazole. MS (ES+) m/e 351.2 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193164B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-15a6bdbc6b9948459b2f51f3dfc5ed2c |
| Source note | uspto-grants-2012_06 |