Piperazin-2-one → 4-{[5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-yl]carbonyl}piperazin-2-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:5]2[cH:6][c:7]([C:8](=[O:9])[N:22]3[CH2:23][C:24](=[O:28])[NH:25][CH2:26][CH2:27]3)[o:10][c:11]2-[c:12]2[cH:13][cH:14][c:15]([F:16])[cH:17][cH:18]2)[cH:19][cH:20][cH:21]1.[Cl:29][c:30]1[cH:31][c:32](-[c:37]2[c:38](-[c:45]3[cH:46][c:47]([Cl:52])[cH:48][c:49]([F:51])[cH:50]3)[cH:39][c:40]([C:42](=[O:43])[OH:44])[o:41]2)[cH:33][cH:34][c:35]1[F:36].[NH:53]1[CH2:54][CH2:55][NH:56][CH2:57][C:58]1=[O:59]>>[N:22]1([C:42]([c:40]2[cH:39][c:38](-[c:45]3[cH:46][c:47]([Cl:52])[cH:48][c:49]([F:51])[cH:50]3)[c:37](-[c:32]3[cH:31][c:30]([Cl:29])[c:35]([F:36])[cH:34][cH:33]3)[o:41]2)=[O:43])[CH2:23][C:24](=[O:28])[NH:25][CH2:26][CH2:27]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-df61c5b6253f4a16b8cff06dd3cb80ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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