HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(N-Boc-amino)piperidine → (4-Amino-piperidin-1-yl)-((R)-3-amino-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Reactant | (R)-3-Amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amide | HCID 67022910 | — |
| Product | (4-Amino-piperidin-1-yl)-((R)-3-amino-pyrrolidin-1-yl)-methanone | HCID 67022950 | — |
Reaction Steps
(4-Amino-piperidin-1-yl)-((R)-3-amino-pyrrolidin-1-yl)-methanone is prepared analogously to (R)-3-amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amide (Intermediate IF) by replacing (4-amino-cyclohexyl)-carbamic acid tert-butyl ester with piperidin-4-yl-carbamic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193164B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-ef73d520d4824a128627fa3b04cf99cd |
| Source note | uspto-grants-2012_06 |