Dimethyl Sulfoxide → 1,2,3,4-tetrahydro[1]benzothieno[2,3-b][1,5]benzothiazepin-12(11H)-one

HRID 2158728Notes

Reaction equation

HRID 2158728 reaction equation
[Br:1][c:2]1[c:3]([C:11](=[O:12])[NH:13][c:14]2[c:15]([SH:20])[cH:16][cH:17][cH:18][cH:19]2)[c:4]2[c:5]([s:6]1)[CH2:7][CH2:8][CH2:9][CH2:10]2.[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][S:28](=[O:29])[CH3:30].[K+:25].[K+:26]>>[c:2]12[c:3]([c:4]3[c:5]([s:6]1)[CH2:7][CH2:8][CH2:9][CH2:10]3)[C:11](=[O:12])[NH:13][c:14]1[c:15]([cH:16][cH:17][cH:18][cH:19]1)[S:20]2

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 184222902-bromo-4,5,6,7-tetrahydro-N-(2-mercaptophenyl)-benzo[b]thiophene-3-carboxamide

Product 1

HCID 184221671,2,3,4-tetrahydro[1]benzothieno[2,3-b][1,5]benzothiazepin-12(11H)-one

Sources & evidence

ORD record
ord-ae083373bc3a4c6d9a6211f8be858613
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…