反应详情

A suspension of 1-methyl-(1-methylethoxy)-5-(phenylmethoxy)-1H-indole-2-carboxamide (2.1 g, 6.2 mmol) in 100 mL of methanol is hydrogenated using 0.5 g of 20% palladium on carbon catalyst. The catalyst is filtered and the filtrate evaporated. Recrystallization of the residue from aqueous acetonitrile gives. 0.87 g (58%) of product; mp 234°-237° C.

1. filtrationThe catalyst is filtered
2. customthe filtrate evaporated
3. customRecrystallization of the residue from aqueous acetonitrile
4. customgives