huagongshe.com
HRID215881

反应详情

EQUATION

反应方程式

HRID 215881 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@H]1C[C@@H](n2cnc3c(N[C@H](CO)Cc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O
HCID57777516

未命名化合物

结构：CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1CC(n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)C(O)C1O
HCID72278799

未命名化合物

结构：N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O.O=C(O)C(F)(F)F
HCID86622631

未命名化合物

PRODUCTS

生成物

1
结构：N[C@H]1C[C@@H](n2cnc3c(N[C@H](CO)Cc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O
HCID86643676

未命名化合物

PROCEDURE

实验过程

(1S,2R,3S,5R)-3-Amino-5-[2-chloro-6-((S)-1-hydroxymethyl-2-phenyl-ethylamino)-purin-9-yl]-cyclopentane-1,2-diol is prepared analogously to (1S,2R,3S,5R)-3-amino-5-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-cyclopentane-1,2-diol trifluoroacetate (Step AAI3) by replacing 1R,2S,3R,5S)-3-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-5-(di-Boc-amino)-cyclopentane-1,2-diol (Step AAI2) with (1R,2S,3R,5S)-3-[2-chloro-6-((S)-1-hydroxymethyl-2-phenyl-ethylamino)-purin-9-yl]-5-(di-Boc-amino)-cyclopentane-1,2-diol (Step TA2).