HCID 68476554, compound → HCID 67023012, compound

Participants

Reaction Steps

((R)-1-{3-[9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-(2-hydroxy-acetylamino)-cyclopentyl}-6-((S)-1-hydroxymethyl-2-phenyl-ethylamino)-9H-purin-2-yl]-prop-2-ynyl]-pyrrolidin-3-yl)-carbamic acid tert-butyl ester (Intermediate XC) is dissolved in 1.25 M HCl in MeOH. After stirring at RT for 3 days, the solvent is removed in vacuo to yield the title compound. This is used in the next step without further purification.

Provenance & Evidence