Bromide ion → 2-Bromo-5-(4-fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyridine
Reaction equation
[Br-:36].[CH2:45]([Cl:46])[Cl:47].[Cl:37][c:38]1[c:39]([Cl:40])[cH:41][cH:42][cH:43][cH:44]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[cH:10][c:11](=[O:18])[nH:12][c:13]2[C:14]([F:15])([F:16])[F:17])[cH:6][cH:7]1.[K+:35].[OH2:48].[P:29]([Br:30])([Br:31])([Br:32])([Br:33])[Br:34]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[cH:10][c:11]([Br:30])[n:12][c:13]2[C:14]([F:15])([F:16])[F:17])[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-bda2fe09f59f4273b95a69757888706e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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