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HRID215956

反应详情

EQUATION

反应方程式

HRID 215956 的结构方程式

REACTANTS

反应物

1
结构：Cc1cc([N+](=O)[O-])cnc1N1CCC2(CC1)CCN([C@H]1CC[C@@H](O)CC1)C2=O
HCID178428769

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(N)cnc1N1CCC2(CC1)CCN([C@H]1CC[C@@H](O)CC1)C2=O
HCID178428568

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Pd/C (15 mg) was added to a solution of 2-(cis-4-hydroxycyclohexyl)-8-(3-methyl-5-nitropyridin-2-yl)-2,8-diazaspiro[4.5]decan-1-one in methanol (5.0 mL) under an atmosphere of nitrogen. The mixture was stirred under an atmosphere of hydrogen for 2 hrs, and filtered. The filtrate was concentrated to give 8-(5-amino-3-methylpyridin-2-yl)-2-(cis-4-hydroxycyclohexyl)-2,8-diazaspiro[4.5]decan-1-one.

WORKUP

后处理

  1. filtrationfiltered
  2. concentrationThe filtrate was concentrated