HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium amide → 5-Methoxy-1-methyl-3-[(1-methylethyl)thio]-1H-indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium amide | HCID 24532 | — |
| Reactant | methyl 5-methoxy-1-methyl-3-[(1-methylethyl)thio]-1H-indole-2-carboxylate | HCID 15294536 | — |
| Product | 5-Methoxy-1-methyl-3-[(1-methylethyl)thio]-1H-indole-2-carboxamide | HCID 15294533 | 68% |
Reaction Steps
Prepared from methyl 5-methoxy-1-methyl-3-[(1-methylethyl)thio]-1H-indole-2-carboxylate and lithium amide as described in Example 23. Yield 68% after recrystallization from ethyl acetate-hexane; mp 122°-124° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05424329 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-a7f979b7f8b24b2c95f16e4a87726e4b |
| Source note | uspto-grants-1995_06 |