tert-Butyl acetate → 3-Oxo-3-[3-[5-methyl-4-(tetrahydro-pyran-2-yloxymethyl)-thiazol-4-yl]-phenyl]-propionic acid tert-butyl ester
Reaction equation
[C:25]([CH3:26])(=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([C:10]2([CH2:16][O:17][CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[N:11]=[CH:12][S:13][CH:14]2[CH3:15])[cH:7][cH:8][cH:9]1)=[O:24].[Li:33]>>[C:3]([c:4]1[cH:5][c:6]([C:10]2([CH2:16][O:17][CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[N:11]=[CH:12][S:13][CH:14]2[CH3:15])[cH:7][cH:8][cH:9]1)(=[O:24])[CH2:26][C:25](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32]Participants
4
Sources & evidence
- ORD record
- ord-459580a7887a4205a2da8f1b0e7e4663
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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