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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2159824Generated: November 2, 2026

Hydrochloric Acid → trans-N-[4-[N-(1-tert-butoxycarbonylpiperidin-4-yl)-N-methylaminomethyl]cyclohexyl]-7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine-4-carboxamide

https://huagongshe.com/reaction/2159824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAcetonitrileHCID 6342—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant7-(4-Methylphenyl)-2,3-dihydrobenzooxepine-4-carboxylic acidHCID 10564699—
Reactanttert-butyl trans-4-[N-(4-aminocyclohexylmethyl)-N-methylamino]piperidine-1-carboxylateHCID 22990074—
Producttrans-N-[4-[N-(1-tert-butoxycarbonylpiperidin-4-yl)-N-methylaminomethyl]cyclohexyl]-7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine-4-carboxamideHCID 9938370—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-a552d4a73f6948f49995238b99e56263
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)