Sodium ion → Tert-butyl 4-[2-(2,3-dihydro-6-nitrospiro[imidazo[2,1-b]oxazol-2,4'-piperidin]-1'-yl)-2-oxoethyl]piperazine-1-carboxylate

HRID 2159967Notes

Reaction equation

HRID 2159967 reaction equation
[Cl:1][c:2]1[n:3]([CH2:10][C:11]2([OH:33])[CH2:12][CH2:13][N:14]([C:17]([CH2:18][N:19]3[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)=[O:32])[CH2:15][CH2:16]2)[cH:4][c:5]([N+:7](=[O:8])[O-:9])[n:6]1.[H-:34].[Na+:35].[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1>>[c:2]12[n:3]([cH:4][c:5]([N+:7](=[O:8])[O-:9])[n:6]1)[CH2:10][C:11]1([CH2:12][CH2:13][N:14]([C:17]([CH2:18][N:19]3[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)=[O:32])[CH2:15][CH2:16]1)[O:33]2

Participants

5

Reactant 4

HCID 923Sodium ionHCID 312751,4-DioxaneHCID 166653HydrideHCID 23081304Tert-butyl 4-{2-[4-(2-chloro-4-nitroimidazol-1-ylmethyl)-4-hydroxypiperidin-1-yl]-2-oxoethyl}piperazine-1-carboxylate

Product 1

HCID 69480722Tert-butyl 4-[2-(2,3-dihydro-6-nitrospiro[imidazo[2,1-b]oxazol-2,4'-piperidin]-1'-yl)-2-oxoethyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-cdc6aa677fa34cb9b8e82ddf932d8425
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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