Oxalic Acid → HCID 68708571, compound

Participants

Reaction Steps

1-[2-(4-Phenyl-[1,2,3]triazol-2-yl)-ethyl]azepane (compound 22) (0.25 mmol) was dissolved in ether (0.5 mL) and mixed with a solution of oxalic acid (0.25 mmol) in AcOEt (0.1 mL) to give 1-[2-(4-Phenyl-[1,2,3]triazol-2-yl)-ethyl]azepanium oxalate as a white precipitate which was filtered off and dried in vacuum. 1H NMR (500 MHz, DMSOd6, 25° C.) δ=8.32 (1H, s), 7.85 (2H, d, 3J=7.4 Hz), 7.47 (2H, t, 3J=7.4 Hz), 7.38 (1H, t, 3J=7.4 Hz), 4.78 (2H, t, 3J=6.2 Hz), 3.52 (2H, sw), 3.09 (4H, sw), 1.70 (4H, sw), 1.55 (4H, sw) ppm. ES-MS m/z=271.0; C18H24N4O4×½ H2O (369.4): caldc. C, 58.52; H, 6.82; N, 15.17. found C, 58.08; H, 6.61; N, 14.71.

Provenance & Evidence