tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate → 2-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid tert-butyl ester
Reaction equation
[C:28]([O:29][C:30]([N:31]1[CH2:32][CH2:33][C:34]2([CH2:35][NH:36][CH2:37]2)[CH2:38][CH2:39]1)=[O:40])([CH3:41])([CH3:42])[CH3:43].[C:44]([CH3:45])([CH3:46])([CH3:47])[O:48][C:49](=[O:50])[N:51]1[CH2:52][CH2:53][C:54]2([CH2:55][N:56]([CH2:58][c:59]3[cH:60][c:61]4[n:62][c:63]([Cl:74])[n:64][c:65]([N:68]5[CH2:69][CH2:70][O:71][CH2:72][CH2:73]5)[c:66]4[s:67]3)[CH2:57]2)[CH2:75][CH2:76]1.[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][C:14]3([CH2:15]1)[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]3)[s:10]2>>[C:44]([CH3:45])([CH3:46])([CH3:47])[O:48][C:49](=[O:50])[N:51]1[CH2:52][CH2:53][C:54]2([CH2:55][N:56]([CH2:58][c:59]3[cH:60][c:61]4[n:62][c:63]([Cl:74])[n:64][c:65]([N:68]5[CH2:69][CH2:70][O:71][CH2:72][CH2:73]5)[c:66]4[s:67]3)[CH2:57]2)[CH2:75][CH2:76]1.[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][C:14]3([CH2:15]1)[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[s:10]2Participants
5
Reactant 3
Product 2
Sources & evidence
- ORD record
- ord-9e2dc95b12eb46328980329fdc5eac6a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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