3-(5,7-Difluoro-4-methyl-3,4-dihydro-2H-chromen-4-yl)-7-[(methylsulfanyl)methyl]-1H-indole → 3-(4-Cyclopropyl-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl)-7-[(methylsulfanyl)methyl]-1H-indole
Reaction equation
[CH3:1][S:2][CH2:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[cH:9][cH:10][nH:11][c:12]12.[CH:13]1([C:16]2([OH:28])[CH2:17][CH2:18][O:19][c:20]3[cH:21][c:22]([F:27])[cH:23][c:24]([F:26])[c:25]32)[CH2:14][CH2:15]1.[F:29][c:30]1[cH:31][c:32]([F:33])[cH:34][c:35]2[c:36]1[C:37]([c:38]1[c:39]3[c:40]([c:41]([CH2:42][S:43][CH3:44])[cH:45][cH:46][cH:47]3)[nH:48][cH:49]1)([CH3:50])[CH2:51][CH2:52][O:53]2>>[CH3:1][S:2][CH2:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[c:9]([C:16]3([CH:13]4[CH2:14][CH2:15]4)[CH2:17][CH2:18][O:19][c:20]4[cH:21][c:22]([F:27])[cH:23][c:24]([F:26])[c:25]43)[cH:10][nH:11][c:12]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4d8371148f564d699ef47dd27ba4792a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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