HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2160815Generated: October 25, 2026
Bicarbonate Ion → 8-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1,4-dioxaspiro[4.5]decane-8-carbonitrile
https://huagongshe.com/reaction/2160815
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bicarbonate Ion | HCID 769 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Carbonate Ion | HCID 19660 | — |
| Reactant | Palladium | HCID 23938 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Dibenzylidene acetone | HCID 95417 | — |
| Reactant | Cesium cation | HCID 104967 | — |
| Reactant | N-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-(trifluoromethyl)pyrimidin-2-amine | HCID 58456089 | — |
| Reactant | 8-(5-Bromo-1,3-thiazol-2-yl)-1,4-dioxaspiro[4.5]decane-8-carbonitrile | HCID 67256979 | — |
| Product | 8-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1,4-dioxaspiro[4.5]decane-8-carbonitrile | HCID 67261700 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
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| ORD ID | ord-658b5bd14c8545b582665c735230d8ec |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
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