4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 59447539, compound

HRID 2161270Notes

Reaction equation

HRID 2161270 reaction equation
[Br:60][c:61]1[cH:62][s:63][c:64]2[c:65]1[n:66][cH:67][n:68][c:69]2[N:70]1[CH2:71][CH2:72][N:73]([CH3:76])[CH2:74][CH2:75]1.[CH3:77][C:78]1([CH3:79])[C:80]([CH3:81])([CH3:82])[O:83][B:84]([c:85]2[cH:86][cH:87][c:88]([OH:91])[cH:89][cH:90]2)[O:92]1.[OH:49][CH2:50][c:51]1[cH:52][cH:53][c:54]([B:55]([OH:56])[OH:57])[cH:58][cH:59]1.[s:1]1[c:2]2[cH:3][cH:4][cH:5][cH:6][c:7]2[n:8][c:9]1[N:10]([CH2:11][O:12][CH2:13][CH2:14][Si:15]([CH3:16])([CH3:17])[CH3:18])[C:19]([c:20]1[cH:21][cH:22][cH:23][c:24]2[c:25]1[CH2:26][N:27]([c:28]1[s:29][c:30](-[c:31]3[cH:32][cH:33][c:34]([CH2:35][OH:36])[cH:37][cH:38]3)[c:39]([C:40]([O:41][CH2:42][CH3:43])=[O:44])[n:45]1)[CH2:46][CH2:47]2)=[O:48]>>[c:61]1(-[c:85]2[cH:86][cH:87][c:88]([OH:91])[cH:89][cH:90]2)[cH:62][s:63][c:64]2[c:65]1[n:66][cH:67][n:68][c:69]2[N:70]1[CH2:71][CH2:72][N:73]([CH3:76])[CH2:74][CH2:75]1

Participants

5

Reactant 4

HCID 27346244-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenolHCID 27347064-(Hydroxymethyl)benzeneboronic acidHCID 59447480ethyl 2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(4-(hydroxymethyl)phenyl)thiazole-4-carboxylateHCID 59447618HCID 59447618, compound

Product 1

HCID 59447539HCID 59447539, compound

Sources & evidence

ORD record
ord-3cbf76edd9d64fe58202ae639bd52e3a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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