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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2161309Generated: November 2, 2026

Tetrahydrofuran → [4-(8-Cyclopropyl-2,2,4,4-tetramethyl-chroman-6-yl-ethvnyl)-2-fluorophenyl]acetic acid ethyl ester

https://huagongshe.com/reaction/2161309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantEthyl 2-fluoro-4-iodophenylacetateHCID 18740710—
Reactant8-Cyclopropyl-6-ethynyl-2,2,4,4-tetramethylchromanHCID 22569006—
Product[4-(8-Cyclopropyl-2,2,4,4-tetramethyl-chroman-6-yl-ethvnyl)-2-fluorophenyl]acetic acid ethyl esterHCID 69548621—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-3a4757f30c8b4524859b5e6ac6f1a494
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)