Acetonitrile → (3-Fluoro-phenyl)-(3,4,5-trifluoro-phenylamino)-acetic acid methyl ester

HRID 2161845Notes

Reaction equation

HRID 2161845 reaction equation
[Br:1][CH:2]([C:3](=[O:4])[O:5][CH3:6])[c:7]1[cH:8][c:9]([F:13])[cH:10][cH:11][cH:12]1.[CH3:24][C:25]#[N:26].[F:14][c:15]1[cH:16][c:17]([NH2:18])[cH:19][c:20]([F:23])[c:21]1[F:22]>>[CH:2]([C:3](=[O:4])[O:5][CH3:6])([c:7]1[cH:8][c:9]([F:13])[cH:10][cH:11][cH:12]1)[NH:18][c:17]1[cH:16][c:15]([F:14])[c:21]([F:22])[c:20]([F:23])[cH:19]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 27249913,4,5-TrifluoroanilineHCID 57495616Methyl 2-bromo-2-(3-fluorophenyl)acetate

Product 1

HCID 58556911(3-Fluoro-phenyl)-(3,4,5-trifluoro-phenylamino)-acetic acid methyl ester

Sources & evidence

ORD record
ord-c936ed47a4a7413c8f53050c42fd9ea7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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