5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 5-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-[3-[4-[(methylamino)methyl]phenyl]-1-pyrrolidinyl]-4-oxo-3-quinolinecarboxylic acid
Reaction equation
[CH3:22][NH:23][CH2:24][c:25]1[cH:26][cH:27][c:28]([CH:31]2[CH2:32][NH:33][CH2:34][CH2:35]2)[cH:29][cH:30]1.[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([F:13])[c:11]1[F:12]>>[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([N:33]2[CH2:32][CH:31]([c:28]3[cH:27][cH:26][c:25]([CH2:24][NH:23][CH3:22])[cH:30][cH:29]3)[CH2:35][CH2:34]2)[c:11]1[F:12]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-71e2325c5a444d84bd22dd022ec33945
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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