Acetic Acid → 3-Amino-3-(6-methylpyridin-3-yl)propan-1-ol

HRID 2162061Notes

Reaction equation

HRID 2162061 reaction equation
[C:28]([OH:29])(=[O:30])[CH3:31].[CH2:1]([N:8]([CH:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:20]1)[CH3:21])[CH:9]([CH2:10][CH2:11][OH:12])[c:13]1[cH:14][n:15][c:16]([CH3:19])[cH:17][cH:18]1)[c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[CH3:32][OH:33].[OH-:34].[OH-:35].[Pd+2:36]>>[NH2:8][CH:9]([CH2:10][CH2:11][OH:12])[c:13]1[cH:14][n:15][c:16]([CH3:19])[cH:17][cH:18]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 178425019HCID 178425019, compound

Product 1

HCID 552924053-Amino-3-(6-methylpyridin-3-yl)propan-1-ol

Sources & evidence

ORD record
ord-da89fe774c244e32a05b2a129a864715
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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