Hydrochloric Acid → N-(tert-butyl)benzohydrazide

Participants

Role	Name	HCID	Charge
Reactant	Hydrochloric Acid	HCID 313	—
Reactant	Sodium Bicarbonate	HCID 516892	—
Reactant	N-t-butoxycarbonyl-N'-benzoyl-N'-t-butylhydrazine	HCID 15767552	—
Product	N-(tert-butyl)benzohydrazide	HCID 1275961	86.7%

Reaction Steps

The N-t-butoxycarbonyl-N'-t-butyl-N'-benzoylhydrazine (52 g, 0.18 mol) was stirred at room temperature in a methanolic hydrochloric acid solution for 4 days. The reaction mixture was neutralized with saturated aqueous sodium bicarbonate. The white precipitate was filtered, washed with water and dried in vacuo to give 30 g of N'-t-butyl-N'-benzoylhydrazine: m.p. 124°-125° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05424333
Source dataset	uspto-grants-1995_06
ORD ID	ord-aee4e2f3b3214f398f75a123d6001f6b
Source note	uspto-grants-1995_06