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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2162304Generated: November 1, 2026

Dimethylformamide → (9-(2-Fluoro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-(2,2,2-trifluoroethyl)thiazol-4-yl)methanone

https://huagongshe.com/reaction/2162304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant2-(2,2,2-Trifluoroethyl)-1,3-thiazole-4-carboxylic acidHCID 57988949—
Reactant2-(3-(1-Oxa-4,9-diazaspiro[5.5]undecan-9-ylmethyl)-2-fluorophenyl)ethanolHCID 57989187—
Product(9-(2-Fluoro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-(2,2,2-trifluoroethyl)thiazol-4-yl)methanoneHCID 57989017—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-87965af4ba6d48358d3e841d1a679c39
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)