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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2162380Generated: November 1, 2026

Dimethylformamide → 10-{[6-Chloro-3-methoxy-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine

https://huagongshe.com/reaction/2162380

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant10,11-Dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepineHCID 15547048—
Reactant2-Chloro-5-methoxy-2′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acidHCID 21947754—
Product10-{[6-Chloro-3-methoxy-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepineHCID 21947798—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-f381ef3455f242cea1c7a65e0a13f4da
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)