Bromide ion → 1-[(3SR,4RS)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethanone

HRID 2162382Notes

Reaction equation

HRID 2162382 reaction equation
[Br-:27].[CH3:1][O:2][N:3]([C:4](=[O:5])[CH:6]1[CH:7]([c:19]2[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]2)[CH2:8][N:9]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:10][CH2:11]1)[CH3:26].[CH3:28][Mg+:29].[CH3:30][O-:31].[CH3:33][OH:34].[Na+:32]>>[C:4](=[O:5])([CH:6]1[CH:7]([c:19]2[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]2)[CH2:8][N:9]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:10][CH2:11]1)[CH3:28]

Participants

7

Reactant 6

HCID 259Bromide ionHCID 887MethanolHCID 923Sodium ionHCID 3826051MethoxideHCID 72299147(3RS,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidine-4-carboxylic acid methoxy-methyl-amideHCID 178477777HCID 178477777, compound

Product 1

HCID 684757041-[(3SR,4RS)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethanone

Sources & evidence

ORD record
ord-3607cb3a66464f478e648b4bca454312
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…