4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide → 9-{4-[4-(8-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Reaction equation
[Cl:28][c:29]1[cH:30][cH:31][cH:32][c:33]2[cH:34][cH:35][c:36]([N:39]3[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]3)[n:37][c:38]12.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:21][CH2:22][CH2:23][CH2:24][Br:25])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]21)([F:26])[F:27]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:21][CH2:22][CH2:23][CH2:24][N:42]2[CH2:41][CH2:40][N:39]([c:36]3[cH:35][cH:34][c:33]4[cH:32][cH:31][cH:30][c:29]([Cl:28])[c:38]4[n:37]3)[CH2:44][CH2:43]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]21)([F:26])[F:27]Participants
3
Sources & evidence
- ORD record
- ord-eae72f5cfa734af1aab8983900ee6a6a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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