7-[2-(1H-indol-5-yloxy)-ethyl]-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester → 7-{2-[1-(2-Ethoxycarbonyl-1-o-tolyl-vinyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH2:24][CH2:25][CH2:26][c:27]2[cH:28][cH:29][c:30]([CH2:33][CH2:34][O:35][c:36]3[cH:37][c:38]4[cH:39][cH:40][nH:41][c:42]4[cH:43][cH:44]3)[n:31][c:32]21.[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[C:6]([c:7]1[c:8]([CH3:13])[cH:9][cH:10][cH:11][cH:12]1)[Cl:14])=[O:15]>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[C:6]([c:7]1[c:8]([CH3:13])[cH:9][cH:10][cH:11][cH:12]1)[n:41]1[cH:40][cH:39][c:38]2[cH:37][c:36]([O:35][CH2:34][CH2:33][c:30]3[cH:29][cH:28][c:27]4[c:32]([n:31]3)[N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:24][CH2:25][CH2:26]4)[cH:44][cH:43][c:42]21)=[O:15]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-cf853cb416fe41f7978c582888e084d9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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