HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418361, compound → HCID 178420779, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | HCID 178525128 | HCID 178525128 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178420779 | HCID 178420779 | — |
Reaction Steps
To a solution of 3-(1H-tetrazol-5-yl)-piperidine-1-carboxylic acid benzyl ester (1 g, 3.5 mmol) in MeOH (20 mL) is added Pd on carbon (10%, 150 mg) at room temperature. The mixture is charged with Ar gas a few times before attaching a hydrogen gas balloon. After 30 h at 20° C., the mixture is filtered, and concentrated to afford 3-(1H-tetrazol-5-yl)-piperidine. LCMS: RT=0.54 minutes, MS: 154 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193183B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-61cf1a94eae24ef196a69773a4fde56f |
| Source note | uspto-grants-2012_06 |