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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 216265Generated: October 29, 2026

HCID 178418361, compound → HCID 178420779, compound

https://huagongshe.com/reaction/216265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178525128HCID 178525128—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178420779HCID 178420779—

Reaction Steps

To a solution of 3-(1H-tetrazol-5-yl)-piperidine-1-carboxylic acid benzyl ester (1 g, 3.5 mmol) in MeOH (20 mL) is added Pd on carbon (10%, 150 mg) at room temperature. The mixture is charged with Ar gas a few times before attaching a hydrogen gas balloon. After 30 h at 20° C., the mixture is filtered, and concentrated to afford 3-(1H-tetrazol-5-yl)-piperidine. LCMS: RT=0.54 minutes, MS: 154 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08193183B2
Source datasetuspto-grants-2012_06
ORD IDord-61cf1a94eae24ef196a69773a4fde56f
Source noteuspto-grants-2012_06