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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2162723Generated: November 2, 2026

proline dl-form → 6-{4-[5-Cyclopropyl-3-(2,6-dichloro-phenyl)-isoxazol-4-ylmethoxy]-piperidin-1-yl}-1-methyl-1H-indole-3-carboxylic acid methyl ester

https://huagongshe.com/reaction/2162723

Reaction equation

Participants

RoleNameHCIDCharge
Reactantproline dl-formHCID 614—
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantCarbonate IonHCID 19660—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantMethyl 6-bromo-1-methyl-1H-indole-3-carboxylateHCID 57443279—
Reactant4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}piperidineHCID 59369334—
Product6-{4-[5-Cyclopropyl-3-(2,6-dichloro-phenyl)-isoxazol-4-ylmethoxy]-piperidin-1-yl}-1-methyl-1H-indole-3-carboxylic acid methyl esterHCID 59369330—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-9fa2e65fec9e4a98ad150e0d07a78cfb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)