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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163045Generated: October 25, 2026

Hydrochloric Acid → 5-{1-[4-(4-Trifluoromethoxy-benzyloxy)-phenyl]-ethylcarbamoyl}-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/2163045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant5-(Methoxycarbonyl)thiophene-2-carboxylic acidHCID 818352—
Reactant1-[4-(4-Trifluoromethoxy-benzyloxy)-phenyl]-ethylamineHCID 58629028—
Product5-{1-[4-(4-Trifluoromethoxy-benzyloxy)-phenyl]-ethylcarbamoyl}-thiophene-2-carboxylic acid methyl esterHCID 69135118—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-f77074f277534a48a7b91902ed29b4e7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)