Methanol → tert-butyl 3-({[4-{[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]carbamoyl}-3-(tetrahydro-2H-pyran-4-ylamino)phenyl]amino}methyl)azetidine-1-carboxylate
Reaction equation
[CH3:54][OH:55].[F:1][c:2]1[cH:3][c:4]([CH2:5][c:6]2[cH:7][c:8]3[c:9]([NH:15][C:16](=[O:17])[c:18]4[c:19]([N:37]([C:38](=[O:39])[C:40]([F:41])([F:42])[F:43])[CH:44]5[CH2:45][CH2:46][O:47][CH2:48][CH2:49]5)[cH:20][c:21]([NH:24][CH2:25][CH:26]5[CH2:27][N:28]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:29]5)[cH:22][cH:23]4)[n:10][nH:11][c:12]3[cH:13][cH:14]2)[cH:50][c:51]([F:53])[cH:52]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][c:6]2[cH:7][c:8]3[c:9]([NH:15][C:16](=[O:17])[c:18]4[c:19]([NH:37][CH:44]5[CH2:45][CH2:46][O:47][CH2:48][CH2:49]5)[cH:20][c:21]([NH:24][CH2:25][CH:26]5[CH2:27][N:28]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:29]5)[cH:22][cH:23]4)[n:10][nH:11][c:12]3[cH:13][cH:14]2)[cH:50][c:51]([F:53])[cH:52]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c9408df8fb3542ca9dbbcf633e12625d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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