HCID 22753856, compound → HCID 22753857, compound
Reaction equation
C(N1CCC(=O)C(C2C=CC=CC=2)C1)CCC.[CH2:18]([N:20]1[CH2:25][CH2:24][C:23](=[O:26])[CH:22]([C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([O:33][CH2:34]CCCC)[CH:28]=2)[CH2:21]1)C.C(N1CC[C@H](O)[C@H](C2C=CC=C(OCCCCC)C=2)C1)C.C(N1CC[C@@H](O)[C@H](C2C=CC=C(OCCCCC)C=2)C1)C>>[CH3:18][N:20]1[CH2:25][CH2:24][CH:23]([OH:26])[CH:22]([C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([O:33][CH3:34])[CH:28]=2)[CH2:21]1Participants
5
Procedure
In a similar manner but replacing 1-methyl-3-(3-methoxylphenyl)-4-piperidone with 1-butyl-3-phenyl-4-piperidone or 1-ethyl-3-(3-pentyloxyphenyl)-4-piperidinone, cis-1-butyl-3-phenyl-4-piperidone, trans-1-butyl-3-phenyl-4-piperidone, cis-1-ethyl-3-(3-pentyloxyphenyl)-4-piperidinol and trans-1-ethyl-3-(3-pentyloxyphenyl)-4-piperidinol are obtained.
Workup
- customare obtained
Sources & evidence
- ORD record
- ord-e0532c492a7d4c0c84da5b090d2fbadf
- Source dataset
- uspto-grants-1979_01
- Patent number
- US04132709
Reaction notes
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