N1-(5-chloro-2-methoxy-4-nitrophenyl)acetamide → 5-Chloro-4-nitro-o-anisidine

Participants

Reaction Steps

0.5 mol (99.5 g) of 2-acetamido-4-chloro-5-nitroanisole and 125 ml of a solution of potassium hydroxide (140 g of KOH/100 ml of water) are introduced into a 500 ml flask; the mixture is brought to between 100 and 110° C for one hour and three quarters; the product is dried without heating and washed with water.

Provenance & Evidence