Acryloyl chloride → HCID 22754353, compound

HRID 2163222Notes

Reaction equation

[NH2:1][C:2]1[N:3]=[C:4]([CH3:7])[S:5][CH:6]=1.[C:8](Cl)(=[O:11])[CH:9]=[CH2:10]>>[C:8]([NH:1][C:2]1[N:3]=[C:4]([CH3:7])[S:5][CH:6]=1)([CH:9]=[CH2:10])=[O:11]

Participants

Reactant 2

HCID 13140Acryloyl chloride

HCID 147727002-Methyl-1,3-thiazol-4-amine

Product 1

HCID 22754353HCID 22754353, compound

Procedure

4-Amino-2-methylthiazole (prepared by hydrolysing 4-acetamido-2-methylthiazole) is treated with acryloylchloride to give the title compound.

Sources & evidence

ORD record: ord-69c8fbde03fa4b609bd41fec168d1176
Source dataset: uspto-grants-1979_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04132798

Reaction notes

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