Pyridine → HCID 70599965, compound

HRID 2163284Notes

Reaction equation

HRID 2163284 reaction equation
Cl[C:2]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[O:14][C:13](=[O:15])[O:12][N:11]=1)=[O:3].O[CH2:17][CH2:18][O:19][C:20](=[O:24])[C:21]([CH3:23])=[CH2:22].N1C=CC=CC=1>O1CCOCC1>[C:20]([O:19][CH2:18][CH2:17][C:2]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[O:14][C:13](=[O:15])[O:12][N:11]=1)=[O:3])(=[O:24])[C:21]([CH3:23])=[CH2:22]

Participants

5

Reactant 3

HCID 1049PyridineHCID 133602-Hydroxyethyl MethacrylateHCID 22753193HCID 22753193, compound

Product 1

HCID 70599965HCID 70599965, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

In accordance with the procedure of Example 1, 35.34g (0.15 moles) 5-(chloroformyloxypentyl)-1,3,4-dioxazol-2-one is reacted with 21.47g (0.165 moles) hydroxyethylmethacrylate in 75 ml 1,4-dioxane by adding 11.86g (0.15 moles) pyridine in 65 ml 1,4-dioxane over a 1 hour period at 19-21° C. After work-up, 47.30g of a slightly brown liquid is obtained which is analyzed by IR and NMR spectroscopy to be 5-[(methacryloyloxyethyl) formyloxypentyl]-1,3,4-dioxazol-2-one (yield 95.7%), having the following formula: ##STR16##

Workup

  1. customAfter work-up, 47.30g of a slightly brown liquid is obtained which

Sources & evidence

ORD record
ord-b3dc14345f0e40d987cd1279a6491b66
Source dataset
uspto-grants-1979_01
Patent number
US04133813

Reaction notes

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